Impact diurnal variations of IOP on dynamic corneal hysteresis measured with air-puff swept-source OCT

Photonics Letters of Poland 2018 | 10 (3) | 64-66

Karol Marian Karnowski, Ewa Mączyńska, Maciej Nowakowski, Bartłomiej Kałużny, Ireneusz Grulkowski, Maciej Wojtkowski


The deformation amplitudes measured with air-puff OCT are sensitive to both (intraocular pressure) IOP and biomechanical properties of the cornea. Amplitudes analysis of corneal deformations is challenging due to interrelation of IOP and corneal biomechanics. In this study, we used natural diurnal IOP fluctuations to investigate corneal deformations in a number of subjects whose eyes were measured multiple times during the day. The results of analysis, based on corneal hysteresis, revealed a corneal hysteresis parameter, which remains constant during the day for each individual eye. We hypothesize that the above-mentioned metric might correlate with biomechanical properties of the cornea without any influence of IOP.

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This project has received funding from the European Union’s
Horizon 2020 research and innovation programme
under grant agreement No 666295.