ICHF HR

Working visit to Max Planck Institute

2018-06-05

Michał Hamkało as a member of the prof. Wojtkowski team took part in a working visit at the Max Planck Institute. The bussines trip was organized in order to perform the first 3D OCT measurements of a beating rabbit hearts (in Langedorrff perfusion system). All measurements were done together by the team of prof. Wojtkowski and their collaborators from Max Planck Institute for Dynamics and Selforganization (dr Jan Christoph, Stephan Luther) in Goettingen and from Institute for Biomedical Optics in Luebeck (T. Pfeiffer, W. Draxonger and prof. Huber).

Team of prof. Wojtkowski have implemented MHz OCT (with use of MHz FDML laser) system into the optical mapping system for heart measurements. Optical mapping is already well-known surface-imaging technique, which allows tracking electrical activity of the heart (during both normal beating and abnormal states) at its surface (and after adding electro-sensitive dye). Due to the fact that this technique allows to obtain 2D images artifacts connected with heart motions are damaging quality of tracking. Thanks to application of MHz OCT system they have done simultaneous measurements of beating heart in both techniques – 3D OCT (100 vol/s) and 2D optical mapping (200 vol/s). Experiments involved 3 different rabbit hearts and acquiring multiple 5-7 s long 3D images stacks of different parts of heart (with rates up to 100 vol/s) together with continuous optical mapping measurements. Two techniques measurements were synchronized with use of TTL-signal triggering. This joint measurements of same area of a beating heart has not been done before, and acquired data after proper processing and interpretation has potential to become an important contribution to cardiological sciences.

Visitor

Michał Hamkało

Dates

April 22-28, 2018

Location

Max Planck Institute, Goettingen, Germany

This project has received funding from the European Union’s
Horizon 2020 research and innovation programme
under grant agreement No 666295.