Two-photon excitation fluorescence (TPEF) imaging of the back of the eye allows visualization of subcellular structures in the living animal eye. This method is helpful for investigating mechanisms of retinal diseases and development of ophthalmic therapies. Endogenous fluorophores, necessary for replenishing visual chromophore, and thus sustaining vision have absorption maxima in the range from 320 – 400 nm. However, anterior optics of the animal eye poorly transmit light at those wavelengths. Two-photon excitation fluorescence imaging employing 75 fs laser pulses overcomes this barrier and visualizes subcellular organelles in the living animal eye.
Working visit to Optical Biomedical Imaging Group Institute of Physics, Nicolaus Co-pernicus University.
The visit to Optical Biomedical Imaging Group Institute of Physics, Nicolaus Copernicus University was to have the deep analysis of the in-vivo imaging of the global mouse brain ischemia (GI) using Bessel beam optical coherence microscopy. This method allows to monitor changes in brain structure with extra control of blood flow during the process of artery occlusion. The results showed the capability and sensitivity of OCM system with Bessel beam to analyze brain plasticity after severe injury within a period of 8 days.
The main goal of the visit was to present the research activity of the Physical Optics and Biophotonics Group to the researchers from Medical University Gdansk and University of Gdansk, get to know their scope of research and search for potential areas of cooperation and common research topics between both the institutions.
On the 20 – 21 Oct., 2016 Professor Pavel Jungwirth from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences came to IPC. On the first day Professor Jungwirth delivered an open for all IPC researchers (incl. PhD students) lecture: “Exploring Hydrated Electrons in Non-Conventional and Conventional Ways: From Alkali Metal Explosions to Non-Explosive Ways”. The lecture was aimed at stimulating creativity and curiosity of the IPC society as regards to selected research topics and drawing inspiration for research from everyday life.